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Article

Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients.

Journal of periodontal research - 1 Dec 2020

Cirelli Thamiris, Nepomuceno Rafael, Rios Ana Cláudia S, Orrico Silvana R P, Cirelli Joni A, Theodoro Letícia H, Barros Silvana P, Scarel-Caminaga Raquel M

Abstract excerpt

OBJECTIVE: To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, "classically" related with periodontitis, could be associated with susceptibility to T2DM, and also with both diseases concomitantly. BACKGROUND: There are common pathogenic mechanisms in type 2 diabetes mellitus (T2DM) and periodontitis, but the knowledge of the genetic aspect...

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PMID: 32648256
DOI: 10.1111/jre.12784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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