Article
Association of type 2 diabetes mellitus and periodontal disease susceptibility with genome-wide association-identified risk variants in a Southeastern Brazilian population.
Clinical oral investigations - 1 Jun 2021
Cirelli Thamiris, Nepomuceno Rafael, Goveia Jéssica Marina, Orrico Silvana R P, Cirelli Joni A, Theodoro Letícia Helena, Barros Silvana P, Scarel-Caminaga Raquel M
Abstract excerpt
OBJECTIVE: Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CDKN2B, RPSAP52, GPR45 HHEX, IL18, and RUNX2 genes associated with type 2 diabetes mellitus (T2DM) and/or periodontitis (P) in diverse populations, and we sought to evaluate them as genetic risk variants for these diseases in the Brazilian population. MATERIAL AND METHODS:...
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