Article
Gene polymorphism of β-defensin-1 is associated with susceptibility to periodontitis in Japanese.
Odontology - 1 Jan 2015
Ikuta Takahisa, Inagaki Yuji, Tanaka Kazuya, Saito Tsuyoshi, Nakajima Yukiko, Bando Mika, Kido Jun-Ichi, Nagata Toshihiko
Abstract excerpt
Periodontitis is a multifactorial disease associated with genetic and environmental factors. Single-nucleotide polymorphisms (SNPs) are associated with susceptibility to common diseases such as diabetes and periodontitis. Although the oral cavity is exposed to various organisms, the conditions are well controlled by innate and acquired immune systems. Antimicrobial peptides (AMPs) play an important role in the...
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