Article
Interleukin-1 gene cluster polymorphisms associated with periodontal disease in type 2 diabetes.
Journal of periodontology - 1 Oct 2009
López Néstor J, Valenzuela Carlos Y, Jara Lilian
Abstract excerpt
BACKGROUND: Epidemiologic studies have shown an increased frequency, severity, and risk of periodontitis in patients with diabetes. Periodontitis is associated with certain interleukin (IL)-1 gene cluster polymorphisms. Diabetes is a proinflammatory state with increased levels of circulating cytokines suggesting a causal role for inflammation in its etiology. Common genetic factors may be involved in the...
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