Article
Interleukin-1 gene cluster polymorphisms associated with periodontal disease in type 2 diabetes.
Journal of periodontology - 1 Oct 2009
López Néstor J, Valenzuela Carlos Y, Jara Lilian
Abstract excerpt
BACKGROUND: Epidemiologic studies have shown an increased frequency, severity, and risk of periodontitis in patients with diabetes. Periodontitis is associated with certain interleukin (IL)-1 gene cluster polymorphisms. Diabetes is a proinflammatory state with increased levels of circulating cyto...
Topics
- Adult
- Age Factors
- Aged
- Alleles
- Case-Control Studies
- Chronic Periodontitis
- Cytosine
- Dental Plaque Index
- Diabetes Mellitus, Type 2
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Gingival Hemorrhage
- Humans
- Interleukin 1 Receptor Antagonist Protein
- Interleukin-1
- Interleukin-1alpha
- Interleukin-1beta