Article
Testing for differences in polygenic scores in the presence of confounding.
Genetics - 4 Jun 2025
Blanc Jennifer, Berg Jeremy J
Abstract excerpt
Polygenic scores have become an important tool in human genetics, enabling the prediction of individuals' phenotypes from their genotypes. Understanding how the pattern of differences in polygenic score predictions across individuals intersects with variation in ancestry can provide insights into the evolutionary forces acting on the trait in question and is important for understanding health disparities....
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