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Article

Research Review: How to interpret associations between polygenic scores, environmental risks, and phenotypes.

Journal of child psychology and psychiatry, and allied disciplines - 1 Oct 2022

Pingault Jean-Baptiste, Allegrini Andrea G, Odigie Tracy, Frach Leonard, Baldwin Jessie R, Rijsdijk Frühling, Dudbridge Frank

Abstract excerpt

BACKGROUND: Genetic influences are ubiquitous as virtually all phenotypes and most exposures typically classified as environmental have been found to be heritable. A polygenic score summarises the associations between millions of genetic variants and an outcome in a single value for each individual. Ever lowering costs have enabled the genotyping of many samples relevant to child psychology and psychiatry...

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Identifiers

PMID: 35347715
DOI: 10.1111/jcpp.13607
PMCID: PMC9790749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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