Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Local patterns of genetic sharing between neuropsychiatric and insulin resistance-related conditions

12 Apr 2025

Abstract excerpt

The co-occurrence of insulin resistance (IR)-related metabolic conditions with neuropsychiatric disorders is a major public health challenge. Evidence of the genetic links between these phenotypes is emerging, but little is currently known about the genomic regions and biological functions that are involved. To address this, we performed Local Analysis of [co]Variant Association (LAVA) using large-scale (N =...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Treatment and Management
Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40221434
DOI: 10.1038/s41398-025-03349-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Local patterns of genetic sharing between neuropsychiatric and insulin resistance-related conditionsPMID 40221434Read ↗

Local patterns of genetic sharing challenge the boundaries between neuropsychiatric and insulin resistance-related conditionsSemantic proximity Read ↗

The multivariate genetic architecture of psychiatric and insulin resistance multimorbiditySemantic proximity Read ↗

The multivariate genetic architecture of psychiatric and insulin resistance multimorbidity.Semantic proximity Read ↗

Shared genetic architecture and bidirectional clinical risks within the psycho-metabolic nexusSemantic proximity Read ↗

Investigating the common genetic architecture and causality of metabolic disorders with neurodegenerative diseases.Semantic proximity Read ↗

Genomic insights into the comorbidity between type 2 diabetes and schizophreniaSemantic proximity Read ↗

Analysis of overlapping genetic association in type 1 and type 2 diabetesSemantic proximity Read ↗

Common and rare genetic variants show network convergence for a majority of human traits.Semantic proximity Read ↗

Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States.Semantic proximity Read ↗

Evidence for Shared Genetic Aetiology Between Schizophrenia, Cardiometabolic, and Inflammation-Related Traits: Genetic Correlation and Colocalization AnalysesSemantic proximity Read ↗

Integrative GWAS identifies novel loci and genetic links between psychiatric and metabolic factors in anorexia nervosa.Semantic proximity Read ↗

Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.