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Shared genetic architecture and bidirectional clinical risks within the psycho-metabolic nexus

27 Dec 2024

Abstract excerpt

BACKGROUND: Increasing evidence suggests a complex interplay between psychiatric disorders and metabolic dysregulations. However, most research has been limited to specific disorder pairs, leaving a significant gap in our understanding of the broader psycho-metabolic nexus. METHODS: This study leveraged large-scale cohort data and genome-wide association study (GWAS) summary statistics, covering 8 common...

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PMID: 39731856
DOI: 10.1016/j.ebiom.2024.105530

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