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Article

Integrative GWAS identifies novel loci and genetic links between psychiatric and metabolic factors in anorexia nervosa.

Molecular psychiatry - 1 Aug 2026

Song Yingchao, Jiang Yue, Tian He, Glessner Joseph, Hakonarson Hakon, Chang Xiao

Abstract excerpt

Anorexia nervosa (AN) is a complex psychiatric disorder with both psychiatric and metabolic underpinnings. This study aims to explore the genetic architecture of AN and the interplay between its psychiatric and metabolic components. Through a meta-analysis of AN GWAS data from European and Finnish populations, we identified a novel genome-wide significant locus near the SOX5 gene. Genetic correlation and...

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Identifiers

PMID: 41927769
DOI: 10.1038/s41380-026-03591-7

Genes

BDNF
LPL
SOX5
VAMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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