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Article

Associations Between APOC3 and ANGPTL8 Gene Polymorphisms With MASLD Risk and the Mediation Effect of Triglyceride on MASLD in the Chinese Population.

Journal of cellular and molecular medicine - 1 Apr 2025

Pan Jia, Wang Xue, Zhang Youjin, Wang Ting, Lv Saiqun, Zhang Xiaoli, Zhou Yuanyuan, Peng Tao, Song Yongyan

Abstract excerpt

Apolipoprotein C3 (APOC3) and angiopoietin-like protein 8 (ANGPTL8) genes are related to lipid metabolism. The relationships between single nucleotide polymorphisms (SNPs) in the APOC3 and ANGPTL8 genes with metabolic dysfunction-associated steatotic liver disease (MASLD) remain controversial. This study aimed to investigate the associations between specific SNPs in the APOC3 and ANGPTL8 genes and MASLD risk,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40192643
DOI: 10.1111/jcmm.70542
PMCID: PMC11974264

Genes

ANGPTL8
APOC3
TG
C3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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