Article
The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population.
Aging - 25 Mar 2022
Yuan Fan, Gu Zhan, Bi Yan, Yuan Ruixue, Niu Weibo, Ren Decheng, Zhang Lei, He Guang, Liu Bao-Cheng
Abstract excerpt
BACKGROUND: Accumulated studies have pointed out the striking association between variants in or near APOC3, GCKR, PNPLA3, and nonalcoholic fatty liver disease (NAFLD) at various ages from multiple ethnic groups. This association remained unclear in the Chinese Han elderly population, and whether this relationship correlated to any clinical parameters was also unclear. OBJECTIVES: This study aims to decipher the...
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