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Article

Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2026

Schwantes-An Tae-Hwi, Abreu Marco A, Neuschwander-Tetri Brent A, Wang Jian, Guo Xiuqing, Tan Jingyi, Hegele Robert A, Davidson Nicholas O, Lotta Luca, Verweij Niek, Yates Katherine P, Rotter Jerome I, Chalasani Naga

Abstract excerpt

BACKGROUND AND AIMS: Dyslipidemia is common in patients with MASLD, but the frequency and significance of inherited disorders of dyslipidemia are unclear. We investigated the prevalence and significance of pathogenic variants associated with selected monogenic disorders of dyslipidemia in 3358 patients with well-characterised MASLD. APPROACH: We identified clinically relevant variants in APOB, MTTP, PCSK9,...

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Topics

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Share to Angiopoietin-Like Protein 3
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41514510
DOI: 10.1111/liv.70486
PMCID: PMC12789714

Genes

LDLR
APOB
ANGPTL3
MTTP
FH
LDLRAP1
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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