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Genetic susceptibility to lung squamous cell carcinoma: new insights on 9q33.2 variants and tobacco smoking.

Carcinogenesis - 3 Apr 2025

Ma Huimin, Wang Guoqing, Miao Sunan, Jin Chen, Cai Jiaying, Ge Wenjing, Zhang Chang, Zhang Erbao, Ma Hongxia, Zhu Meng

Abstract excerpt

Genome-wide association studies (GWAS) have identified over 60 susceptibility loci for lung cancer, yet the biological mechanisms underlying these associations remain largely unknown, particularly for lung squamous cell carcinoma (LUSC). Here, we integrated data from 3890 LUSC cases and 13 328 controls of Chinese descent, and performed a conditional analysis to explore independent genetic variants and analyzed...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40168134
DOI: 10.1093/carcin/bgaf018

Genes

ZBTB26
FOXA1
PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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