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Genome-wide gene-smoking interaction study identified novel susceptibility loci for non-small cell lung cancer in Chinese populations.

Carcinogenesis - 5 Oct 2021

Wang Yuzhuo, Ji Mengmeng, Zhu Meng, Fan Jingyi, Xie Junxing, Huang Yanqian, Wei Xiaoxia, Jiang Xiangxiang, Xu Jing, Chen Liang, Yin Rong, Wang Cheng, Zhang Ruyang, Zhao Yang, Dai Juncheng, Jin Guangfu, Hu Zhibin, Christiani David C, Ma Hongxia, Xu Lin, Shen Hongbing

Abstract excerpt

Gene-smoking interactions play important roles in the development of non-small cell lung cancer (NSCLC). To identify single-nucleotide polymorphisms (SNPs) that modify the association of smoking behavior with NSCLC risk, we conducted a genome-wide gene-smoking interaction study in Chinese populations. The genome-wide interaction analysis between SNPs and smoking status (ever- versus never-smokers) was carried out...

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Source

Identifiers

PMID: 34297049
DOI: 10.1093/carcin/bgab064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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