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Abnormal epigenetic modification of lysosome and lipid regulating genes in Alzheimer’s disease

28 Mar 2025

Abstract excerpt

Background Abnormal lipid metabolism has been identified as a potential pathogenic mechanism of Alzheimer's disease (AD), which might be epigenetically regulated. Lysosomes are critical organelles for lipid metabolism. However, the epigenetic modifications of lysosome and lipid regulating genes remain unclear in AD patients. Objective Explore the role of abnormal epigenetic modifications, especially methylation...

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PMID: 40151896
DOI: 10.1177/13872877251322955

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