Article
Identification of lipid metabolism-related genes and their roles in Alzheimer’s disease: a multi-omics analysis
2023-07-20
Abstract excerpt
<h4>Background: </h4> Alzheimer's disease (AD) is a neurological condition that worsens with time. It is distinguished by the buildup of improperly folded amyloid beta protein, which produces amyloid plaques and promotes tau protein aggregation into neurofibrillary tangles in the brain. Certain lipids are critically involved in the development of AD, for instance, apolipoprotein E (ApoE), which is involved in lipi...
Topics
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- Alzheimer's disease research and treatments
- Atherosclerosis and Cardiovascular Diseases
- Bioinformatics and Genomic Networks
- Computational Drug Discovery Methods
- Dementia and Cognitive Impairment Research
- Metabolomics and Mass Spectrometry Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- be3a5f52-4138-5091-bb81-b2a8ea5ddbc6
- DOI
- 10.21203/rs.3.rs-3174585/v1
