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Article

Down-regulation of SORL1 is associated with Alzheimer's disease through activating ABC transporter pathway.

Zeitschrift fur Naturforschung. C, Journal of biosciences - 26 May 2021

Wei Zhiqiang, Qi Xingdi, Zhai Shijun, Chen Yan, Xia Xiaoshuang, Zheng Boyu, Sun Xugang, Zhang Guangming, Wang Ling, Zhang Qi, Xu Chen, Jiang Shihe, Li Xiulian, Xie Bingxin, Liao Xiaohui, Ai Zhu, Li Xin

Abstract excerpt

Alzheimer's disease (AD) is a common neurodegenerative disease with high morbidity among elderly people. A genetic attribution has been extensively proved. Here, we propose to further prioritize genes that harbor single nucleotide variation (SNV) or structural variation (SV) for AD and explore the underlying potential mechanisms through exploiting their expression and methylation spectra. A high-confidence...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33909958
DOI: 10.1515/znc-2019-0213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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