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Histone Methylation, Energy Metabolism, and Alzheimer's Disease

1 Jan 2024

Abstract excerpt

Alzheimer's disease (AD) is an insidious, progressive, and irreversible neurodegenerative disease characterized by the deposition of extracellular amyloid β-protein (Aβ) to form senile plaques and abnormal phosphorylation of intracellular tau protein to form neuronal fiber tangles. The pathogenesis of AD is complex, and there are several hypotheses, primarily including the Aβ cascade hypothesis, the...

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PMID: 39656495
DOI: 10.14336/ad.2024.0899

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