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Article

Characterizing Rare DNA Copy-Number Variants in Pediatric Obsessive-Compulsive Disorder.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jul 2026

Abdallah Sarah B, Olfson Emily, Cappi Carolina, Greenspun Samantha, Zai Gwyneth, Rosário Maria C, Willsey A Jeremy, Shavitt Roseli G, Miguel Euripedes C, Kennedy James L, Richter Margaret A, Fernandez Thomas V

Abstract excerpt

OBJECTIVE: Pediatric obsessive-compulsive disorder (OCD) is a common neuropsychiatric disorder in which genetic factors play an important role. Recent studies have demonstrated an enrichment of rare de novo DNA single-nucleotide variants in persons with OCD compared to controls, and larger studies have examined copy-number variants (CNVs) using microarray data. Our study examines rare de novo CNVs using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40122455
DOI: 10.1016/j.jaac.2025.03.014
PMCID: PMC12353602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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