Article
High resolution chromosomal microarray analysis in paediatric obsessive-compulsive disorder.
BMC medical genomics - 28 Nov 2017
Grünblatt Edna, Oneda Beatrice, Ekici Arif B, Ball Juliane, Geissler Julia, Uebe Steffen, Romanos Marcel, Rauch Anita, Walitza Susanne
Abstract excerpt
BACKGROUND: Obsessive-Compulsive Disorder (OCD) is a common and chronic disorder in which a person has uncontrollable, reoccurring thoughts and behaviours. It is a complex genetic condition and, in case of early onset (EO), the patients manifest a more severe phenotype, and an increased heritability. Large (>500 kb) copy number variations (CNVs) previously associated with autism and schizophrenia have been...
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