Article

Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder

2024-03-13

Abstract excerpt

Obsessive-compulsive disorder (OCD) affects ∼1% of children and adults and is partly caused by genetic factors. We conducted a genome-wide association study (GWAS) meta-analysis combining 53,660 OCD cases and 2,044,417 controls and identified 30 independent genome-wide significant loci. Gene-based approaches identified 249 potential effector genes for OCD, with 25 of these classified as the most likely causal cand...

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Literature Corpus work: 6b6003b6-dd57-5ce0-a199-8cdf2bf233de
DOI: 10.1101/2024.03.13.24304161

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