Genetic background of selected hyperuricemia causing gout with pediatric onset.

Abstract excerpt

Elevated serum uric acid levels are the essential pathophysiology of gout. Although gout rarely develops in childhood, chronic persistent hyperuricemia can induce precipitation and deposition of sodium urate crystals, leading to the development of gout. Hyperuricemia is caused by increased uric acid production and/or decreased uric acid excretion capacity of the kidneys and/or intestinal tract. Increased...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Age of Onset
• Share to Child
• Share to Genetic Predisposition to Disease