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Aging, Senescence, and Dementia

21 Apr 2022

Abstract excerpt

The underlying processes occurring in aging are complex, involving numerous biological changes that result in chronic cellular stress and sterile inflammation. One of the main hallmarks of aging is senescence. While originally the term senescence was defined in the field of oncology, further research has established that also microglia, astrocytes and neurons become senescent. Since age is the main risk factor...

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PMID: 35841253
DOI: 10.14283/jpad.2022.42

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