Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polyphosphatases have a polyphosphate-independent influence on the virulence of Cryptococcus neoformans

12 Mar 2025

Abstract excerpt

ABSTRACT Cryptococcus neoformans, an invasive basidiomycete fungal pathogen, causes one of the most prevalent, life-threatening diseases in immunocompromised individuals and accounts for ~19% of AIDS-associated deaths. Therefore, understanding the pathogenesis of C. neoformans and its interactions with the host immune system is critical for developing therapeutics against cryptococcosis. Previous studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal Infections and Studies
Share to Phytochemical compounds biological activities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40071953
DOI: 10.1128/iai.00072-25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polyphosphatases have a polyphosphate-independent influence on the virulence of Cryptococcus neoformansPMID 40071953Read ↗

Defects in phosphate acquisition and storage influence virulence of Cryptococcus neoformans.Semantic proximity Read ↗

Sac1 links phosphoinositide turnover to cryptococcal virulenceSemantic proximity Read ↗

Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformansSemantic proximity Read ↗

Sac1 links phosphoinositide turnover to cryptococcal virulenceSemantic proximity Read ↗

Proteomics of Cryptococcus neoformans: From the Lab to the ClinicSemantic proximity Read ↗

Lipid Flippase Mediated Membrane Asymmetry Governs Extracellular Vesicles Biogenesis and Host Interactions in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Peeling the onion: the outer layers of Cryptococcus neoformansSemantic proximity Read ↗

The enigmatic role of fungal annexins: the case of <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Lack of an atypical PDR transporter generates an immunogenic <i>Cryptococcus neoformans</i> strain that drives a dysregulated and lethal immune response in murine lungsSemantic proximity Read ↗

Bacterial polyphosphates interfere with the innate host defense to infection.Semantic proximity Read ↗

Polyphosphate Kinase 2 (PPK2) Enzymes: Structure, Function, and Roles in Bacterial Physiology and VirulenceSemantic proximity Read ↗

Cryptococcus and Beyond—Inositol Utilization and Its Implications for the Emergence of Fungal VirulenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.