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Cryptococcus and Beyond—Inositol Utilization and Its Implications for the Emergence of Fungal Virulence

13 Sept 2012

Abstract excerpt

There are over one million fungal species in nature, but only a handful of them cause human diseases. A variety of distinct factors aid the virulence of fungi in their transition from environmental reservoirs to mammals. One important factor is their ability to acquire nutrients efficiently so that they can survive and thrive in a nutrient-limiting host environment. The human fungal pathogen Cryptococcus...

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PMID: 23028304
DOI: 10.1371/journal.ppat.1002869

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