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Article

Feedback-resistant acetohydroxy acid synthase increases valine production in Corynebacterium glutamicum.

Applied and environmental microbiology - 1 Jan 2005

Elisáková Veronika, Pátek Miroslav, Holátko Jirí, Nesvera Jan, Leyval Damien, Goergen Jean-Louis, Delaunay Stéphane

Abstract excerpt

Acetohydroxy acid synthase (AHAS), which catalyzes the key reactions in the biosynthesis pathways of branched-chain amino acids (valine, isoleucine, and leucine), is regulated by the end products of these pathways. The whole Corynebacterium glutamicum ilvBNC operon, coding for acetohydroxy acid synthase (ilvBN) and aceto hydroxy acid isomeroreductase (ilvC), was cloned in the newly constructed Escherichia coli-C....

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Identifiers

PMID: 15640189
DOI: 10.1128/AEM.71.1.207-213.2005
PMCID: PMC544200

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Source receipt: pubmed, retrieved 7 Sept 2026.

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