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Article

Mutations in the microexon splicing regulator srrm4 have minor phenotypic effects on zebrafish neural development.

G3 (Bethesda, Md.) - 8 May 2025

Gupta Tripti, Margolin Gennady, Burgess Harold A

Abstract excerpt

Achieving a diversity of neuronal cell types and circuits during brain development requires alternative splicing of developmentally regulated mRNA transcripts. Microexons are a type of alternatively spliced exon that are 3-27 nucleotides in length and are predominantly expressed in neuronal tissues. A key regulator of microexon splicing is the RNA-binding protein Serine/arginine repetitive matrix 4 (Srrm4). Srrm4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40053833
DOI: 10.1093/g3journal/jkaf052
PMCID: PMC12060237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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