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Article

Embryo-scale reverse genetics at single-cell resolution.

Nature - 1 Nov 2023

Saunders Lauren M, Srivatsan Sanjay R, Duran Madeleine, Dorrity Michael W, Ewing Brent, Linbo Tor H, Shendure Jay, Raible David W, Moens Cecilia B, Kimelman David, Trapnell Cole

Abstract excerpt

The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from whole embryos1-4. A majority of these data, however, has been collected from wild-type embryos without an appreciation for the latent variation that is present in development. Here we present the 'zebrafish single-cell atlas of perturbed embryos': single-cell transcriptomic data from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37968389
DOI: 10.1038/s41586-023-06720-2
PMCID: PMC10665197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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