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Article

Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development.

Genes & development - 1 Apr 2015

Quesnel-Vallières Mathieu, Irimia Manuel, Cordes Sabine P, Blencowe Benjamin J

Abstract excerpt

Alternative splicing (AS) generates vast transcriptomic complexity in the vertebrate nervous system. However, the extent to which trans-acting splicing regulators and their target AS regulatory networks contribute to nervous system development is not well understood. To address these questions, we generated mice lacking the vertebrate- and neural-specific Ser/Arg repeat-related protein of 100 kDa (nSR100/SRRM4)....

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Source

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Identifiers

PMID: 25838543
DOI: 10.1101/gad.256115.114
PMCID: PMC4387716

Genes

SRRM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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