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Elucidating the Linkage Between Obesity‐Related Body Fat Indicators and Atrial Fibrillation: Supported by Evidence From Mendelian Randomization and Mediation Analyses

1 Mar 2025

Abstract excerpt

ABSTRACT Objectives To elucidating the linkage between obesity‐associated body fat indicators and atrial fibrillation (AF) using Mendelian Randomization (MR) and mediation analysis. Methods The study utilized three independent genome‐wide association study (GWAS) datasets, with containing over 450 000 individuals each, to represent body fat indicators as the exposure variable. Additionally, two summary genetic...

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Share to Atrial Fibrillation Management and Outcomes
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PMID: 40045506
DOI: 10.1002/clc.70103

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