Article
Associations of 50 modifiable risk factors with atrial fibrillation using Mendelian randomization analysis.
European journal of clinical investigation - 1 Jun 2024
Zhang Zhuxin, Li Le, Zhang Zhenhao, Hu Zhao, Xiong Yulong, Zhou Likun, Yao Yan
Abstract excerpt
BACKGROUND: Substantial focus has been placed on atrial fibrillation (AF) treatment and associated stroke prevention rather than preventing AF itself. We employed Mendelian randomization (MR) approach to examine the causal relationships between 50 modifiable risk factors (RFs) and AF. METHODS: Instrumental variables for genetically predicted exposures were derived from corresponding genome-wide association...
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