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Article

Associations of 50 modifiable risk factors with atrial fibrillation using Mendelian randomization analysis.

European journal of clinical investigation - 1 Jun 2024

Zhang Zhuxin, Li Le, Zhang Zhenhao, Hu Zhao, Xiong Yulong, Zhou Likun, Yao Yan

Abstract excerpt

BACKGROUND: Substantial focus has been placed on atrial fibrillation (AF) treatment and associated stroke prevention rather than preventing AF itself. We employed Mendelian randomization (MR) approach to examine the causal relationships between 50 modifiable risk factors (RFs) and AF. METHODS: Instrumental variables for genetically predicted exposures were derived from corresponding genome-wide association...

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Identifiers

PMID: 38438337
DOI: 10.1111/eci.14194

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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