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Article

Causality of abdominal obesity on cognition: a trans-ethnic Mendelian randomization study.

International journal of obesity (2005) - 1 Aug 2022

Wang Shi-Heng, Su Mei-Hsin, Chen Chia-Yen, Lin Yen-Feng, Feng Yen-Chen A, Hsiao Po-Chang, Pan Yi-Jiun, Wu Chi-Shin

Abstract excerpt

BACKGROUND: Obesity has been associated with cognition in observational studies; however, whether its effect is confounding or a reverse causality remains inconclusive. This study aimed to investigate the causal relationships of overall obesity, measured by body mass index (BMI), and abdominal adiposity, measured by waist-hip ratio adjusted for BMI (WHRadjBMI), and cognition across European and Asian populations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35538205
DOI: 10.1038/s41366-022-01138-8

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