Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessing the genetic overlap between BMI and cognitive function.

Molecular psychiatry - 1 Oct 2016

Marioni R E, Yang J, Dykiert D, Mõttus R, Campbell A, Davies G, Hayward C, Porteous D J, Visscher P M, Deary I J

Abstract excerpt

Obesity and low cognitive function are associated with multiple adverse health outcomes across the life course. They have a small phenotypic correlation (r=-0.11; high body mass index (BMI)-low cognitive function), but whether they have a shared genetic aetiology is unknown. We investigated the phenotypic and genetic correlations between the traits using data from 6815 unrelated, genotyped members of Generation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Body Mass Index
Share to Cognition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genome-Wide Association Study

Share to Multifactorial Inheritance

Share to Obesity

Share to Scotland

Source

Open in PubMed Open full text

Identifiers

PMID: 26857597
DOI: 10.1038/mp.2015.205
PMCID: PMC4863955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessing the genetic overlap between BMI and cognitive function.PMID 26857597Read ↗

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia.Semantic proximity Read ↗

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.Semantic proximity Read ↗

Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study.Semantic proximity Read ↗

Cognitive ability and physical health: a Mendelian randomization studySemantic proximity Read ↗

Cognitive ability and physical health: a Mendelian randomization studySemantic proximity Read ↗

Shared genetic aetiology between cognitive ability and cardiovascular disease risk factors: Generation Scotland's Scottish family health studySemantic proximity Read ↗

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.Semantic proximity Read ↗

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Semantic proximity Read ↗

Associations between obesity indices and cognitive function: Evidence from a middle-aged observational and Mendelian randomisation study.Semantic proximity Read ↗

Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.Semantic proximity Read ↗

Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).Semantic proximity Read ↗

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.