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Article

The relationship between adiposity and cognitive function: a bidirectional Mendelian randomization study in UK Biobank.

International journal of epidemiology - 2 Aug 2023

Norris Tom, Salzmann Antoine, Henry Albert, Garfield Victoria, Pinto Pereira Snehal M

Abstract excerpt

BACKGROUND: There may be a bidirectional relationship between cognition and adiposity, whereby poor cognition leads to increased adiposity and vice versa. We aimed to determine whether these findings are causal, by undertaking a bidirectional Mendelian randomization (MR) study. METHODS: A total of 378 877 UK Biobank participants had three adiposity indicators [body fat percentage (BF%), body mass index (BMI) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37029912
DOI: 10.1093/ije/dyad043
PMCID: PMC10396406

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