Self‐reactive B cells are increased in all major stages of peripheral development in Sjögren's disease

Abstract excerpt

Abstract Sjögren's disease (SjD) is a chronic autoimmune disorder characterized by increased circulating self‐reactive B cells. While many of these self‐reactive B cells emerge from the bone marrow, it is not known whether they are excluded from or enriched in specific developmental stages in the periphery. The aim of this study was to determine the immunophenotype of circulating self‐reactive B cells in SjD to...

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