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Article

Association Analysis of the Circulating Proteome With Sarcopenia‐Related Traits Reveals Potential Drug Targets for Sarcopenia

1 Feb 2025

Abstract excerpt

ABSTRACT Background Sarcopenia severely affects the physical health of the elderly. Currently, there is no specific drug available for sarcopenia. This study aims to identify pathogenic proteins and druggable targets for sarcopenia through Mendelian randomization (MR)–based analytical framework. Methods A sequential stepwise screening method that includes two‐sample MR, Steiger filtering test and colocalization...

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PMID: 39949133
DOI: 10.1002/jcsm.13720

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