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Article

A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration.

Scientific reports - 8 Feb 2025

Yang Hongfan, Huang Haofei, Pu Kunlin

Abstract excerpt

Age-related macular degeneration (AMD) is a complex multifactorial disease with a significant genetic component. Despite extensive research efforts, the underlying molecular mechanisms remain elusive, necessitating innovative approaches to identify specific genes involved in the pathogenesis of AMD and to elucidate their functional mechanisms. A transcriptome-wide association study (TWAS) was conducted by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39922885
DOI: 10.1038/s41598-025-89246-z
PMCID: PMC11807202

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