Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networks

24 Feb 2012

Abstract excerpt

UNLABELLED: Please see related commentary: http://www.biomedcentral.com/1741-7015/10/21/abstract BACKGROUND: Age-related macular degeneration (AMD) is a leading cause of blindness that affects the central region of the retinal pigmented epithelium (RPE), choroid, and neural retina. Initially characterized by an accumulation of sub-RPE deposits, AMD leads to progressive retinal degeneration, and in advanced cases,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma and retinal disorders
Share to Ophthalmology and Visual Impairment Studies
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22364233
DOI: 10.1186/gm315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systems-level analysis of age-related macular degeneration reveals global biomarkers and phenotype-specific functional networksPMID 22364233Read ↗

Age-Related Macular Degeneration: Cellular and Molecular Signaling MechanismsSemantic proximity Read ↗

A ten-gene retinal pigment epithelium (RPE)/choroid complex diagnosis signature for age-related macular degenerationSemantic proximity Read ↗

Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular DegenerationSemantic proximity Read ↗

Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration.Semantic proximity Read ↗

Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profilingSemantic proximity Read ↗

Pathway activation profiling reveals new insights into age-related macular degeneration and provides avenues for therapeutic interventions.Semantic proximity Read ↗

A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration.Semantic proximity Read ↗

The ocular tissue-specificity of differentially expressed age-related macular degeneration associated genesSemantic proximity Read ↗

Transcriptome-wide analysis of differentially expressed chemokine receptors, SNPs, and SSRs in the age-related macular degenerationSemantic proximity Read ↗

Identification of cellular and molecular risk signatures for progression to late-stage age-related macular degeneration using the 9-step Minnesota Grading SystemSemantic proximity Read ↗

Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease.Semantic proximity Read ↗

Identification of Immune-related Core Genes Based on Immune Signatures of Age-related Macular DegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.