Article
Genome-wide association analyses identify 139 loci associated with macular thickness in the UK Biobank cohort.
Human molecular genetics - 1 Apr 2019
Gao X Raymond, Huang Hua, Kim Heejin
Abstract excerpt
The macula, located near the center of the retina in the human eye, is responsible for providing critical functions, such as central, sharp vision. Structural changes in the macula are associated with many ocular diseases, including age-related macular degeneration (AMD) and glaucoma. Although macular thickness is a highly heritable trait, there are no prior reported genome-wide association studies (GWASs) of it....
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