Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HGF/c‐Met Promotes Breast Cancer Tamoxifen Resistance Through the EZH2/HOTAIR‐miR‐141/200a Feedback Signaling Pathway

24 Jan 2025

Abstract excerpt

Tamoxifen is one of the most frequently used endocrine medications for the treatment of estrogen receptor-positive (ER + ) breast cancer (BC). Unfortunately, tamoxifen resistance (TR) brings more challenges to the clinical treatment, and the mechanisms of TR have not yet been fully clarified. HGF/c-Met is closely associated with cancer metastasis, but whether it is involved in TR remains unclear. In our study, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cytokine Signaling Pathways and Interactions
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39853766
DOI: 10.1002/mc.23878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HGF/c‐Met Promotes Breast Cancer Tamoxifen Resistance Through the EZH2/HOTAIR‐miR‐141/200a Feedback Signaling PathwayPMID 39853766Read ↗

The Met receptor tyrosine kinase: a key player in oncogenesis and drug resistance.Semantic proximity Read ↗

HGF/c-MET pathway in cancer: from molecular characterization to clinical evidenceSemantic proximity Read ↗

Aberrations of c-MET drive breast cancer metastasis in an HGF-dominant environmentSemantic proximity Read ↗

Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast CarcinomaSemantic proximity Read ↗

[Status quo of research on HGFc-Met signaling pathway in cancers].Semantic proximity Read ↗

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunitiesSemantic proximity Read ↗

HGF/c-MET Axis in Tumor Microenvironment and Metastasis FormationSemantic proximity Read ↗

The MET Oncogene Network of Interacting Cell Surface ProteinsSemantic proximity Read ↗

Targeting the c-Met Signaling Pathway in CancerSemantic proximity Read ↗

Molecular mechanism(s) of regulation(s) of c-MET/HGF signaling in head and neck cancerSemantic proximity Read ↗

An Introduction and Overview of RON Receptor Tyrosine Kinase SignalingSemantic proximity Read ↗

Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.