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Article

Comprehensive Analysis of the Expression and Prognostic Value of SPINT1/2 in Breast Carcinoma

26 Jul 2021

Abstract excerpt

Background: Hepatocyte growth factor (HGF) signaling plays a plethora of roles in tumorigenesis and progression in many cancer types. As HGF activator inhibitors, serine protease inhibitor, Kunitz types 1 and 2 (SPINT1 and SPINT2) have been reported to be differentially expressed in breast cancer, but their prognostic significance and functioning mechanism remain unclear. Methods: In our study, multiple databases...

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PMID: 34381422
DOI: 10.3389/fendo.2021.665666

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