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Article

Harnessing the Immunotherapy Revolution for the Treatment of Childhood Cancers.

Cancer cell - 10 Apr 2017

Majzner Robbie G, Heitzeneder Sabine, Mackall Crystal L

Abstract excerpt

Cancer immunotherapies can be classified into agents that amplify natural immune responses (e.g., checkpoint inhibitors) versus synthetic immunotherapies designed to initiate new responses (e.g., monoclonal antibodies [mAbs], chimeric antigen receptors [CARs]). Checkpoint inhibitors mediate unprecedented benefit in some adult cancers, but have not demonstrated significant activity in pediatric cancers, likely due...

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Identifiers

PMID: 28366678
DOI: 10.1016/j.ccell.2017.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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