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Article

Assays to enhance metabolic phenotyping in the kidney.

American journal of physiology. Renal physiology - 1 Apr 2025

Hammoud Safaa, Kern Justin, Mukherjee Sandip, Lutkewitte Andrew J, Singh Prabhleen, Newberry Kate, Finck Brian N, Gewin Leslie S

Abstract excerpt

The kidney is highly metabolically active, and injury induces changes in metabolism that can impact repair and fibrosis progression. Changes in the expression of metabolism-related genes and proteins provide valuable data, but functional metabolic assays are critical to confirm changes in metabolic activity. Stable isotope metabolomics is the gold standard, but these involve considerable cost and specialized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39819047
DOI: 10.1152/ajprenal.00232.2024
PMCID: PMC12145867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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