Article
Multi-omics and imaging mass cytometry characterization of human kidneys to identify pathways and phenotypes associated with impaired kidney function.
Kidney international - 1 Jul 2024
Asowata Evans O, Romoli Simone, Sargeant Rebecca, Tan Jennifer Y, Hoffmann Scott, Huang Margaret M, Mahbubani Krishnaa T, Krause Fynn N, Jachimowicz Daniel, Agren Rasmus, Koulman Albert, Jenkins Benjamin, Musial Barbara, Griffin Julian L, Soderberg Magnus, Ling Stephanie, Hansen Pernille B L, Saeb-Parsy Kourosh, Woollard Kevin J
Abstract excerpt
Despite the recent advances in our understanding of the role of lipids, metabolites, and related enzymes in mediating kidney injury, there is limited integrated multi-omics data identifying potential metabolic pathways driving impaired kidney function. The limited availability of kidney biopsies from living donors with acute kidney injury has remained a major constraint. Here, we validated the use of deceased...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.