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Article

How do immune cells shape type 1 diabetes? Insights from Mendelian randomization.

Frontiers in endocrinology - 1 Jan 2024

Yu Yunfeng, Yang Xinyu, Deng Juan, Wu Jingyi, Bai Siyang, Yu Rong

Abstract excerpt

Objective: The role of immune cells in type 1 diabetes (T1D) is unclear. The aim of this study was to assess the causal effect of different immune cells on T1D using Mendelian randomization (MR). Methods: A dataset of immune cell phenotypes (numbered from GCST0001391 to GCST0002121) was obtained from the European Bioinformatics Institute, while a T1D dataset (numbered finngen_R10_T1D) was obtained from FinnGen....

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Share to Dendritic Cells
Share to Diabetes Mellitus, Type 1
Share to CD4 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 39777226
DOI: 10.3389/fendo.2024.1402956
PMCID: PMC11703746

Genes

CD28
CD4
CD80

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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