Article
Causal relationship between circulating immune cells and inflammatory bowel disease: A Mendelian randomization analysis.
Medicine - 26 Jul 2024
Li Shan, Mao Dujuan, Hao Quanshui, You Lijuan, Li Xiufang, Wu Yaohua, Wei Lai, Du Heng
Abstract excerpt
Inflammatory bowel disease (IBD) is an immune-mediated inflammation of the gastrointestinal tract that includes Crohn disease and ulcerative colitis (UC). Although IBD is associated with elevated levels of innate and adaptive immunity, the relationship between circulating immune cells and IBD remains largely unknown. Therefore, we conducted a bidirectional 2-sample Mendelian randomization (MR) study to determine...
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