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Article

Use of designer recombinant mitochondrial antigens in the diagnosis of primary biliary cirrhosis

1 Mar 1992

Abstract excerpt

The appearance of autoantibodies against mitochondria in patients with primary biliary cirrhosis has been known for more than 25 yr. In the past, based on the biochemical complexity of the mitochondrion and the use of crude extracts for immunodiagnosis, a degree of nonspecificity in assaying for antibodies to mitochondria has been present. This problem has been largely circumvented by the cloning of the...

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PMID: 1371979
DOI: 10.1002/hep.1840150302

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