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Article

Association of Reduced Folate Carrier G80A Polymorphism With Lung Cancer Susceptibility in a Hypertensive Population: A Nested Case-Control Study.

The Journal of nutrition - 1 Feb 2025

He Qiangqiang, Wei Yaping, Zhu Hehao, Song Yun, Chen Ping, Dong Qing, Ma Hai, Wang Binyan, Zhang Yan, Li Jianping, Huo Yong, Shi Hanping, Dong Yuhan

Abstract excerpt

BACKGROUND: Polymorphisms of the folate-associated one-carbon metabolism (OCM) pathway genes may regulate certain susceptibilities to cancer. G80A, a polymorphism in the reduced folate carrier (RFC) gene, may be associated with cancer risk, although the results obtained from previous studies have been inconsistent. OBJECTIVES: This study aimed to evaluate the association of G80A with lung cancer among a Chinese...

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PMID: 39740751
DOI: 10.1016/j.tjnut.2024.12.023

Genes

OCM

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