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Article

The Role of Sex Hormones and Sex Hormone-binding Globulin in Functional Gatrointestinal Disorders: A Bidirectional Two-sample Mendelian Randomization Study.

Journal of gastrointestinal and liver diseases : JGLD - 28 Dec 2024

Fan Zhengyang, Shao Changming, Kou Zhifu, Xie Feng, Wang Hongyu, Zheng Shuai, Wen Bo, Chen Zheng, Zeng Binfang

Abstract excerpt

BACKGROUND AND AIMS: Sex hormones and sex hormone-binding globulin (SHBG) have been confirmed to involve in the pathophysiology of functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome (IBS) and functional dyspepsia (FD). However, causal associations have not yet been investigated. Utilizing data from Genome-wide association studies, we conducted bidirectional two-sample mendelian...

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PMID: 39733319
DOI: 10.15403/jgld-5642

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SHBG

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