Article
Associations between sex hormones, receptors, binding proteins and inflammatory bowel disease: a Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Zou Fei, Hu Yaxian, Xu Mengmeng, Wang Su, Wu Zengrong, Deng Feihong
Abstract excerpt
Background: Gender differences existed in inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC). Observational studies have revealed associations between sex hormones and IBD, such as estrogen and testosterone. However, the exact relationship between these sex hormones and IBD is unclear. Method: Based on the genome-wide association studies data of eight sex hormones, two...
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